Skin Inflammation and PK of Azithromycin
ConditionSkin Infection
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorMedical University of Vienna
About this trial
This study will investigate the tissue distribution of azithromycin in healthy, artificially inflamed and actually infected tissue of humans.
Eligibility criteria
Qualifiers
• Men and women aged ≥18 and <55 years
BMI ≥18 and ≤30 kg/m2
Normal (or clinically irrelevant abnormal) findings in medical history and physical examination
Women with child-bearing potential: use of effective contraception
Disqualifiers
Known or suspected allergy to lipopolysaccharide, imiquimod, or sticking plasters
Only Part 0c: Known or suspected allergy to local anesthetics
History of severe allergic or anaphylactic reactions to any medication • Blood donation within the last 4 weeks before the study
Treatment with an investigational drug within three weeks before the study
Trial design
Treatments tested in this trial
- Azithromycin
- Biopsy
- Skin inflammation model
Treatment groups
36 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov