Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorThe Cleveland Clinic
About this trial
A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe obstructive sleep apnea (OSA).
Eligibility criteria
Qualifiers
Informed consent
Age 18-85 years
High burden paroxysmal AF (≥1%)
Moderate-severe OSA (AHI ≥ 15)
Disqualifiers
AF ablation <6 months
Valvular abnormalities
Excessive daytime sleepiness in safety-critical jobs
Plans for ablation during study
Trial design
Treatments tested in this trial
- CPAP
Treatment groups
20 Participants
are divided into 1 treatment groupSponsors and collaborators
The Cleveland Clinic
Lead sponsor
University of Washington
Collaborator
Source ClinicalTrials.gov