Sleep-dependent Learning in Aging
ConditionSleep
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Massachusetts, Amherst
About this trial
The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.
Eligibility criteria
Qualifiers
Age 18-80 yrs
Healthy sleeper
No diagnosed sleep or neurodegenerative disorder
Disqualifiers
Past diagnosis of any sleep disorder or evidence of a sleep disorder as assessed by self-reported sleep quality assessments, a standardized diagnostic interview, and an acclimation night of polysomnography. Using acclimation-night polysomnography, participants will be excluded with an Apnea-Hypopnea Index >15; a Period-Limb Movement in Sleep index of >15/hr; sleep-onset latency > 45 min (indicative of insomnia); or sleep efficiency < 80% (see Edinger et al., Sleep, 2004). In cases in which questions arise regarding a participants' inclusion or sleep records, a practicing neurologist board-certified in sleep medicine will review the documentation.
Past diagnosis neurological illness or head injury
Reported average sleep per night < 5 or > 9 hrs
Current employment involving shift work or an inability to keep a regular sleep schedule during the week prior to testing
Trial design
Treatments tested in this trial
- Sleep
Treatment groups
584 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov