Smart Underwear to Measure Diet-Induced Hydrogen Sulfide Production
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Colorado, Denver
About this trial
The purpose of this study is to evaluate the ability of a wearable Smart Underwear prototype device to quantify diet-induced changes in gut microbial hydrogen sulfide (H₂S) production. The core design is a single-site, 2-period, crossover feeding study with 6-day diet periods and an approximately 11-day washout period. Participants are fed each of two isocaloric diets designed to contrast gut microbial H₂S production (i.e., a high cysteine vs. low cysteine diet), in a random order.
Eligibility criteria
Qualifiers
None
Disqualifiers
Generally healthy volunteers defined as having no major known health conditions (e.g., diabetes, cancer, hypertension, etc.).
Normal bowel movements, with approximately 1 bowel movement reported per day
Willing to discuss flatus
Ages >18yrs
Trial design
Treatments tested in this trial
- High Cysteine Diet
- Low Cysteine Diet
Treatment groups
25 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Colorado, Denver
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
University of Maryland, College Park
Collaborator
Source ClinicalTrials.gov