Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age4+
SponsorIRCCS Eugenio Medea
About this trial
The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients affected by Becker (BMD) and Duchenne (DMD) muscular dystrophy, compared with a sample of patients affected by osteogenesis imperfecta (OI), and both compared with a control sample with typical development.
The secondary aim is to study cortical activity at rest, by means of electroencephalography (EEG), to explore frequencies and time course of EEG responses. Moreover, the relationship between EEG activity and neuropsychological, dispositional and subjective measures will be explored through correlational analyses.
Eligibility criteria
Qualifiers
Patients diagnosed with Duchenne and Becker muscular dystrophy (genetic and histological diagnosis and clinical diagnosis) (ambulant and non-ambulant).
Patients diagnosed with osteogenesis imperfecta.
Control group: participants without any neurological or psychiatric disorder
Disqualifiers
presence of comorbid diagnoses,
sensory deficit
specific condition that could prevent the application of the tests and tasks under study, such as: a) the need for PEG; b) the need for tracheostomy; c) the need for assisted ventilation.
cognitive level lower than 60.
Trial design
Treatments tested in this trial
- Electroencephalography (EEG)
- Social Cognition Tasks
Treatment groups
45 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov