Social-cognitive Functioning: Validation of a New Neuropsychological Test

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

It is now established that disturbances in social cognition are frequent in neurology and that they contribute to the development of social conduct disorders. Their assessment is therefore essential, particularly in order to propose early and adapted care. However, this assessment remains limited today. A new serious game-type test, REALSoCog, has been developed to address the shortcomings of current tools and to highlight disturbances in social behaviors. The latter are not always observed in consultation although they are often reported by caregivers. The objective of this research is therefore to validate the REALSoCog task in a pathological population (currently being standardized in the general population: CER-U, IRB N°: 00012020-115). The clinical interest of this task will be tested with a group of patients suffering from a neurodegenerative disease (Alzheimer's disease (AD), dementia with Lewy bodies (DCL), fronto-temporal lobar degeneration (FTD)) in order to assess its sensitivity and specificity in the detection of social-cognitive disturbances, and in particular in terms of social behaviors (detection of social behavioral disorders reported in daily life). The objective is also to document the socio-cognitive profiles in the mentioned diseases thanks to a more ecological test, and to better understand the links between socio-cognitive processes on the one hand, and individual characteristics on the other hand (e.g. mood and social participation).

Eligibility criteria

Qualifiers

Patient aged between 18 and 90 years

Mini Mental State Examination (MMSE) score greater than or equal to 20

Patient able to express his or her non-opposition to participate in the study in an informed and autonomous manner

Patient with a neurodegenerative pathology: FTD, AD or LBD.

Disqualifiers

Neurological or psychiatric comorbidity

Notable sensory disorders (e.g., profound or total deafness, age-related macular degeneration, blindness, etc.) that may interfere with experimental completion.

Opposition to participation in the study

Trial design

Treatments tested in this trial

  • REALSOCOG
  • BCS
  • Hetero-questionnaires

Treatment groups

120 Participants
are divided into 2 treatment groups