About this trial
The goal of this clinical trial is to determine if a self-selected high potassium diet is easier to achieve and more effective at improving vascular health than a low sodium diet in generally healthy young adults who typically consume more than the recommended amount of sodium. The main questions it aims to answer are:
1. Is it easier for young adults to increase their potassium intake, rather than reduce their sodium intake? 2. Is a self-selected high potassium diet better at improving vascular health compared to a self-selected low sodium diet?
Researchers will compare the effectiveness of an education-based intervention centered only on increasing dietary potassium intake against an education-based intervention centered only on reducing dietary sodium intake.
Participants will be randomly assigned to receive comprehensive dietary education on adopting either a high-potassium diet or a low-sodium diet.
Education will be delivered in four weekly one-on-one sessions. Following the four-week education period, participants will be encouraged to change their diet based on what they have learned. Measures of dietary compliance (urine samples and diet records) and cardiovascular health (blood pressure, endothelial function) will be assessed at two, four, and six months post-education.
Eligibility criteria
Qualifiers
Willing and able to attend in-person laboratory visits
Usual sodium intake ≥3,000 mg/d for females and ≥4,000 mg/d for males
Usual potassium intake ≤2,500 mg/d in females and ≤3,000 mg/d in males
Disqualifiers
BMI ≥35 kg/m2
Seated blood pressure ≥130/80 mmHg
Current diagnosis or history of diabetes, renal disease, cancer, cardiovascular disease, or major cardiovascular event (e.g. heart attack or stroke)
Current or recent use of a diuretic (within the past 6 months)
Trial design
Treatments tested in this trial
- High potassium dietary education/counseling
- Low sodium dietary education/counseling
Treatment groups
Sponsors and collaborators
Florida State University
Lead sponsor
United States Department of Agriculture (USDA)
Collaborator