Health Trials

Soluble and Osmotic Fibre (SOLOS) Diet for Constipation

ConditionsConstipationConstipation - FunctionalConstipation Chronic IdiopathicConstipation Predominant Irritable Bowel SyndromeConstipation, Signs and Symptoms, DigestiveConstipation-predominant IBS (IBS-C)Constipation-predominant Irritable Bowel SyndromeConstipation-predominant Irritable Bowel Syndrome (IBS-C)Diet TherapyDiet ModificationDiet, Food and NutritionDietary and Nutritional TherapiesDietary FiberDietary Fibers
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorSingapore Institute of Technology

About this trial

This research aims to study the dual effectiveness of incorporating soluble fibre and osmotic carbohydrates (SOLOS), with or without restricting fructans and GOS, and present novel findings in managing GI symptoms in patients with functional bowel disorders with constipation. These findings may also support researchers and clinicians in shaping new dietary approaches in the management of general constipation symptoms.

Eligibility criteria

Qualifiers

Presented with symptoms of FC, IBS-C, or SIBO-C

Were aged 18 to 70 years old. (Research focus is on adult patients, excluding older adults and children)

Date of baseline (first) and follow-up appointments ranged from January 2021 to December 2025

Did not attend follow-up appointments (Data would be treated as "intention to treat" and data points were carried forward for conservative analysis).

Disqualifiers

Had no history of constipation-related symptoms (Does not relate to research question's population or outcome)

Started treatment before January 2021

Were not due for follow-up before the end of December 2025

Symptom and stool data inadequately recorded

Trial design

Treatments tested in this trial

  • Diet

Treatment groups

180 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Singapore Institute of Technology

Lead sponsor

Source ClinicalTrials.gov