Somesthesia in Cancer Patients: Variability and Influence on Eating Experience

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorHospices Civils de Lyon

About this trial

Patients with cancer are at high risk of denutrition, in France 39% of these patients suffer of malnutrition. This can affect the immunity, the mental balance and impact the treatment response and the quality of life.

Cancer treatments cause many side effects related to food intake as well as sensory alteration, important factor contributing to reduced appetite and inadequate food intake to cancer patients.

SOMEST'ALIM2 is a prospective, non-randomized, monocentric, multisite study that aims to evaluate the appreciation of patients with different types of cancer (digestive, gynecological, breast, ear, nose and throat (ENT) or lung) of two different food versions (sweet and salty), in standard and enhanced version.

Patients must be under treatment from at least two months, and before food testing their sensory capacity and quantity and the quality of their saliva will be tested. They will also be asked to answer to different questionnaires: socio-demographics, appreciation of food samples, self-assessment of oral symptoms and sensory perceptions, MD, Quality of Life Questionnaire (QLQ-C30) and food quality of life questionnaire.

In a context of sensory alterations patients should appreciate more the enhanced food versions. Patients perception of food will be evaluated using a visual analogue scale and results will be correlated with saliva characteristics, subjective sensory perceptions and oral symptoms.

Eligibility criteria

Qualifiers

Patient between 18 and 70 years old

Patient with digestive, breast, gynecologic, ENT or lung cancer

Patient receiving a cancer treatment from at least two months

Patient having given his free, informed and express written consent

Disqualifiers

Patient having a radiotherapy treatment for an ENT cancer

Patient with a known food allergy/intolerance to food samples (which may contain dairy products)

Patient unable to swallow soft food

Patient having presented nausea and vomiting during the last 24 hours

Trial design

Treatments tested in this trial

  • Salivary test
  • Food tasting
  • Questionnaires
  • sensory capacity evaluation

Treatment groups

96 Participants
are divided into 1 treatment group

Sponsors and collaborators