Spasticity in SCI Following Acute Intermittent Hypoxia
ConditionSpinal Cord Injuries (SCI)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorZev Rymer
About this trial
This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury. It is hypothesized that hypoxia will decrease the reflex threshold of the biceps brachii, indicating an increase in spasticity following the AIH.
Eligibility criteria
Qualifiers
Age >= 18
Non-progressive spinal Cord injury at least 6 months prior
Level of injury between C1-C8
ISNCSCI ASIA classification C or D
Disqualifiers
Pre-existing hypoxic pulmonary disease
Positive Covid-Pneumonia diagnosis within 1 year of visit
Uncontrolled hypertension >140/90 mmHg
Individuals who are currently pregnant/nursing or planning on becoming pregnant
Trial design
Treatments tested in this trial
- Acute Intermittent Hypoxia (AIH)
Treatment groups
10 Participants
are divided into 1 treatment groupSponsors and collaborators
Zev Rymer
Lead sponsor
Shirley Ryan AbilityLab
Sponsor institution
Source ClinicalTrials.gov