Spatiotemporal tSCS in Spinal Cord Injury
ConditionSpinal Cord Injuries (SCI)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16-65
SponsorWashington University School of Medicine
About this trial
Spinal cord injury leads to long-lasting impairment, and currently, there is no cure for paralysis. Although transcutaneous spinal cord stimulation has shown promising results in recovering lost movements, its poor selectivity in muscle recruitment compared to invasive approaches limits the type of rehabilitation exercises that can be practiced. This project studies how spatial, frequency, and amplitude control of stimulation can be used to selectively target different neural pathways and muscle groups.
Eligibility criteria
Qualifiers
Age between 16 and 65 years.
Have a spinal cord injury (neurological level C3-T12) that occurred ≥1 year (chronic stage) prior to enrollment.
American Spinal Injury Association (ASIA) Impairment Scale (AIS) classification C or D
Able to voluntarily contract (motor score ≥ 1) at least two leg muscles (visual or palpable contraction).
Disqualifiers
Progressive spinal lesions, including degenerative disorders of the spinal cord
Pregnant, planning to become pregnant, or currently breastfeeding
History of cardiopulmonary disease or cardiac symptoms
Implanted stimulators of any type (baclofen pump, epidural spinal stimulator, cardiac defibrillator, pace-maker, etc.)
Trial design
Treatments tested in this trial
- No Stimulation
- Conventional tSCS
- Spatiotemporal tSCS
Treatment groups
48 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov