The goal of this project is to develop and validate a reproducible scorecard for the neurological assessment of patients with leptomeningeal metastases that can be used in clinical trials including such patients, as well as in clinical practice.
Adult patients (18 years or more), female or male
Histologically confirmed diagnosis of extra-CNS primary solid cancer
Diagnosis of leptomeningeal metastases confirmed or probable per EANO ESMO criteria
Performance status compatible with enrolment into clinical trials
Inability to give informed consent
Inability to adhere to recommended follow-up according to the treating physician
University of Zurich
Lead sponsor
M.D. Anderson Cancer Center
Collaborator
The Netherlands Cancer Institute
Collaborator