StereoEEG Motor Neuronal Potentials Decoding

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorResearch Center of Neurology, Russia

About this trial

The goals of this study are (1) to evaluate the rate of stereoEEG brain-computer interface (BCI) classification accuracy and (2) to collect the dataset of neuronal signals recorded from stereoEEG electrodes during motor performance, motor imagery or brain-computer interface control. The study enrolls hospitalised patients suffering from resistant epilepsy with already implanted intracranial stereoEEG electrodes for medical reasons (i.e. for preoperative localization of the epileptogenic foci). The number and location of electrodes are determined solely for the clinical purposes of stereoEEG monitoring and are not related to the protocol of the current study.

After obtaining informed consent to participate in the study, each patient will participate in one experimental session lasting no more than 60 minutes, recording brain signals associated with hand movement, motor imagery, and BCI control. All tasks and instructions presented during the study session are not pro-epileptogenic and cannot provoke an epileptic attack. The experiments will take place in the patient's room, without interruption of observation by the department's medical staff.

The data recorded in this study will be used to improve or develop new algorithms for decoding motor signals from deep brain structures for their potential use in invasive BCIs.

Eligibility criteria

Qualifiers

male and female patients who have had stereoEEG electrodes implanted for medical reasons;

voluntary informed consent to participate in the study;

age from 18 to 70 years.

Disqualifiers

patient refusal to participate in the study;

cognitive impairment that prevents following the study instructions;

severe visual impairment that does not allow viewing visual instructions on a computer screen;

upper limb paresis or other motor disorders;

Trial design

Treatments tested in this trial

  • motor tasks

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators

Research Center of Neurology, Russia

Lead sponsor

Institute of Higher Nervous Activity and Neurophysiology of RAS

Collaborator