Stereotactic Post-operative Radiotherapy for Intraparotid Metastatic Cutaneous Squamous Cell Carcinoma
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDavid Palma
About this trial
The purpose of this study is to compare the effectiveness and side effects of stereotactic radiotherapy (5 sessions) against conventional (standard) radiotherapy (20-30 sessions) for the treatment of skin cancer involving the head and neck after surgical resection.
Stereotactic radiotherapy works in the same way that conventional (standard) radiotherapy does to kill cancer cells by damaging their genetic material and stopping the cancer cells from making copies of themselves.
This study will help the study doctors find out if this different approach is the same, better, or worse than the standard of care for your cancer.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Patient able to provide informed consent
Eastern Cooperative Oncology Group (ECOG) performance status 0-2
Patient is a candidate for curative intent treatment
Disqualifiers
Definite metastatic disease at diagnosis
Pregnant or breastfeeding women
Significant health conditions or contraindications to receiving surgery and radiation
History of previous head and neck cancer within 5 years, except for localized skin cancers (i.e. no nodal or distant spread)
Trial design
Treatments tested in this trial
- SBRT
- Standard Radiation
Treatment groups
90 Participants
are divided into 2 treatment groupsSponsors and collaborators
David Palma
Lead sponsor
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sponsor institution
Source ClinicalTrials.gov