About this trial
The goal of this clinical trial is to learn if partial meniscal replacement can prevent or postpone total meniscal replacement, in adult patients (female/male) with partial meniscal loss. The main questions it aims to answer are:
* Can partial meniscal replacement improve knee function? * Can partial meniscal replacement prevent/postpone total meniscal replacement/knee prothesis? Researchers will compare the results of the operated group with patients not willing to be operated but with partial meniscal loss to see if the operation improves knee function.
Participants will be operated and have to attend follow-up visits with MRI after 6 months up to 5 years after surgery.
Eligibility criteria
Qualifiers
Partial loss of portions of the
lateral meniscus and lateral joint line pain OR
medial meniscus and medial joint line pain
sufficient standing of the peripheral rim, so that the procedure can be performed
Disqualifiers
The presence of anterior cruciate ligament insufficiency which is not resolved by reconstruction of the anterior cruciate ligament within 16 weeks after partial meniscal implantation.
Axial deviation (>2° varus or valgus)
realignment osteotomy not performed within 12 weeks
advanced cartilage damage (grade III according to ICRS) and osteoarthrosis in the affected compartment (grade III according to Kellgren and Lawrence [33])
Trial design
Treatments tested in this trial
- Spongioflex®
- non-operated
Treatment groups
Sponsors and collaborators
Sven Behrendt
Lead sponsor
Privatpraxis für Knie- und Schulterchirurgie
Sponsor institution