Stimulant and Polysubstance Use, Inflammation, and Sex Effects on Myocardial Disease in HIV

ConditionHIV (Human Immunodeficiency Virus)

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age30+

SponsorUniversity of California, San Francisco

About this trial

This observational research study is studying how substance use impacts scarring and inflammation of the heart. This study involves one study visit for a cardiac MRI.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Standard contraindications to MRI

claustrophobia,

metal implants,

large body size (weight >350 lbs or abdominal sagittal diameter >70 cm),

Trial population

Participants with and without HIV enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) Atlanta, Baltimore, Bronx, and San Francisco study sites

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

400 Participants

are grouped into 3 trial groups

Group A: Current Stimulant Use

Group B: Past Stimulant Use

Group C: No Stimulant use

Trial outcomes

Primary outcomes

Cardiac MRI

CMR assessments to provide detailed myocardial characterization (e.g. diffuse inflammation (nT1), myocardial fibrosis (ECV), and myocardial scar assessed using LGE)

Time frame

Visit 1, up to 2 hours

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of California, San Francisco

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: