Stimulation-Induced Changes in Fronto-Limbic Network
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Alabama at Birmingham
About this trial
The purpose of this research is to better understand how emotion processing unfolds in the brain using stereoelectroencephalography (sEEG) and direct brain stimulation. This study will use standard behavioral emotion processing tasks combined with neural recording and direct brain stimulation to assess different aspects of emotion processing. Stimulation pulses during pre and post-test periods will assess the effects of stimulation before and after conditioning, the results of which will be combined with results from the activity of each electrode during the emotion tasks to inform us of the nature of emotion processing in the brain and allow us to devise brain modulation protocols in the future.
Eligibility criteria
Qualifiers
1) implantation of sEEG electrodes for SOC epilepsy surgery evaluation
2) cognitive ability to perform simple tasks and to understand instructions
3) implanted electrodes in the amygdala and medial PFC regions
4) competency to understand and sign a written informed consent.
Disqualifiers
1) an inability to complete the task
Trial design
Treatments tested in this trial
- Electrical Pulse Train Stimulation
Treatment groups
30 Participants
are divided into 1 treatment groupSponsors and collaborators
University of Alabama at Birmingham
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov