Strategy for Prompt and Effective Thoracentesis in the Emergency Department
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Aarhus
About this trial
The SPEEDTAP-trial is a prospective, randomised, investigator-initiated, multicenter, clinical superior trial investigating two thoracentesis methods in four emergency departments (ED) in Central Denmark Region. Patients are randomised to either manual fluid removal in the ED or passively fluid drainage using gravity in the radiology department (standard of care). Primary outcome: time from clinical indication to complete drainage and 188 patients will be included. Key secondary outcomes include length of stay, ED admission to ED discharge and safety end-points.
Eligibility criteria
Qualifiers
Patients ≥ 18 years admitted to the ED
Pleural effusion detected by any imaging modality (e.g., bedside ultrasound, chest x-ray, computed tomography)
Clinically justified need for thoracentesis ( symptomatic relief and/or define the etiology of the effusion
Without contraindication for thoracentesis in the emergency department (e.g., anticoagulant treatment)
Disqualifiers
Life-threatening respiratory distress
Not able to give consent
Previous pleurodesis
Effusion does not appear free-flowing due to septations or loculations / suspected empyema
Trial design
Treatments tested in this trial
- Gravity fluid drainage in the radiology department
- Manual drainage in the emergency department
Treatment groups
188 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Aarhus
Lead sponsor
Central Denmark Region
Collaborator
Source ClinicalTrials.gov