About this trial
The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether circulating vehicles of inter-organ communication (extracellular vesicles) and their cargo might help explain those responses. The investigators will also examine whether resveratrol supplementation improves blood vessel function and cognitive function (brain health) in response to strength training.
Eligibility criteria
Qualifiers
Age 60+
Minimally active (less than 1 hour of structured exercise/week other than walking)
No resistance training for the previous 6 months
Not currently taking resveratrol supplements
Disqualifiers
Medical complications that could increase risk during exercise (e.g., cardiovascular disease, uncontrolled hypertension, type 1 or 2 diabetes, orthopedic contraindication to exercise, kidney disease, etc.)
Cannabis or nicotine use
Consume more than 7 alcohol-containing beverages per week
Trial design
Treatments tested in this trial
- Resistance training
- Resveratrol 500 mg oral once daily.
- Placebo
Treatment groups
Sponsors and collaborators
Texas Tech University
Lead sponsor
National Strength and Conditioning Association
Collaborator