Stress & Self-Control Costs

ConditionSelf-Control
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorNYU Langone Health

About this trial

Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms underlying these costs are unknown. To address this, the investigators will use a validated decision-making task that measures how much individuals will pay (from a study endowment) to restrict access to tempting rewards that may lead to self-control failures. The investigators will examine these costs to identify their cognitive, neural and affective mechanisms. First, the investigators will identify the cognitive and computational mechanism that gives rise to self-control costs. Second, the investigators will characterize the neural correlates of self-control costs and identify neural mediators and connectivity patterns stemming from these costs. Finally, the investigators will examine how different classes of stressors (physical, social, or lifetime stress) shape the behavioral and neural representations of self-control costs.

Eligibility criteria

Qualifiers

18-70 years of age, able to speak, read, and write fluently in English

be willing and able to follow study procedures and provide informed consent.

Must additionally confirm they are on a diet to maintain/lose weight and are implementing/maintaining dietary changes.

Disqualifiers

History of or medication for neurologic or psychiatric disease

High-blood pressure or heart condition

Diabetes, food allergies, metabolic disorders or history of eating disorder

Use of corticosteroids or beta-blockers

Trial design

Treatments tested in this trial

  • Cold-Pressor Task (CPT)
  • Trier Social Stress Test (TSST)
  • Modified Non-Stress CPT
  • Modified Non-Stress TSST
  • Functional Magnetic Resonance Imaging (fMRI)

Treatment groups

300 Participants
are divided into 4 treatment groups

Sponsors and collaborators

NYU Langone Health

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator