Striated Esophageal Motor Function Modulation in Health and Disease
ConditionDysphagia, Esophageal
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorMedical College of Wisconsin
About this trial
The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.
Eligibility criteria
Qualifiers
Healthy subjects aged 18 to 90 years.
Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification.
Disqualifiers
Anyone less than 18 years old.
Patients with recent head and neck cancer (<1 month post-surgery or <3 months post-chemo radiation.
Patients suffering from muscle diseases like muscular dystrophies, myopathies.
Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
Trial design
Treatments tested in this trial
- Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction
- Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Treatment groups
557 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov