Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorAalborg University Hospital
About this trial
The investigators aim to elucidate characteristics of structural and functional brain connectivity in patients with amyotrophic lateral sclerosis (ALS) and pseudobulbar affect (PBA) using diffusion kurtosis imaging (DKI) and magnetoencephalography (MEG).
Eligibility criteria
Qualifiers
Diagnosed with ALS in the last 6 months according to Gold Coast Criteria
Disqualifiers
- Lack of ability to answer survey through own ability or through a surrogate, for example by hand controlled, eye-controlled computer and/or tablet, or through telephone interview.
Lack of ability to cooperate.
Pregnancy
Drug addiction defined as the non-prescribed use of cannabis, opioids, or other narcotics.
Trial design
Treatments tested in this trial
- Diffusion Kurtosis Imaging (DKI)
- Resting State Magnetoencephalography
Treatment groups
50 Participants
are divided into 3 treatment groupsSponsors and collaborators
Aalborg University Hospital
Lead sponsor
University of Aarhus
Collaborator
Source ClinicalTrials.gov