Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier William Morey - Chalon sur Saône

About this trial

29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality.

It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias.

The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.

Eligibility criteria

Qualifiers

Patient or relative informed of the study and having declared their non-objection

Patient over 18 years old

Patient hospitalized in ICU with an arterial catheter

Disqualifiers

Patient unable to express consent

Patient whose collection of the arterial catheter is impossible or for whom storage at 4°C is impossible

Patient with arterial catheter removed outside the usual procedure of the ICU

Patient admitted in ICU with an arterial catheter already in place

Trial design

Treatments tested in this trial

  • OCT-BIO-KTA cohort

Treatment groups

60 Participants
are divided into 1 treatment group

Sponsors and collaborators

Centre Hospitalier William Morey - Chalon sur Saône

Lead sponsor

Centre Hospitalier Universitaire Dijon

Collaborator

Centre Hospitalier Macon

Collaborator