The major objective of this study is to evaluate the efficacy of the MACT versus the AMT for the treatment of large cartilage defects in patellofemoral and femorotibial injuries.
Patients aged between 15-50 years
Symptomatic chondral and osteochondral defect, grade III and IV according to the ICRS classification, and size between 2.5 and 15 cm2
Failure of a conservative treatment
Patient in good general condition, documented by an ASA score ≤ 2 (American Society of Anesthesiologists)
All inflammatory and synovial pathologies
Diffuse or mirror lesions
An unfavorable biomechanical environment
Obesity grade II or higher, with a BMI>35 kg/m2
Centre Hospitalier Universitaire Vaudois
Lead sponsor
Virginie PHILIPPE
Collaborator
Lee Ann LAURENT APPLEGATE
Collaborator