Study for Prevent Chronification Migraine Through Prediction of Response to Treatment With Anti-CGRP Antibodies

ConditionMigraine
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorFundación de Investigación Biomédica - Hospital Universitario de La Princesa

About this trial

Being able to predict each patients response to a specific treatment can mean a significant improvement in socioeconomic costs, but above all in their quality of life. With the present study, the investigators aim to analyze in a combined way different clinical, biological and neuroimaging variables, which allow the clinical staff to anticipate the response to treatment with anti-CGRP monoclonal antibodies in patients with migraine.

Eligibility criteria

Qualifiers

Patients aged between 18 and 65 years.

Caucasian ethnicity.

Patients diagnosed with migraine with and without high-frequency episodic aura (more than 8 days of migraine per month) or chronic by a neurologist expert in headaches and according to the criteria proposed in the International Classification of Headache Diseases, 3rd edition (ICHD- 3).

Have at least one year of history of migraine.

Disqualifiers

Patients who present with another type of non-migraine headache, with the exception of headache due to excessive use of analgesic medication.

Neurological focus in the examination.

Pregnancy or breastfeeding period.

Patients with cognitive deficiency or pathology that may prevent or hinder the correct completion of the study.

Trial design

Treatments tested in this trial

  • Headache record
  • Scales
  • Monoclonal antibody anti-CGRP

Treatment groups

350 Participants
are divided into 1 treatment group