This study intends to further evaluate the efficacy of acupuncture by comparing the intervention effects of different acupuncture treatment regimens on hot flashes in breast cancer ; and to explore the central effect regulation mechanism of acupuncture intervention on hot flashes based on integrated PET/MRI technology.
Aged 30-75 years old;
Adjuvant hormone therapy (eg, tamoxifen and/or aromatase inhibitors) with or without ovarian function suppression has been administered for at least 4 weeks and is currently on treatment;
Patients with persistent hot flashes for at least 4 weeks and with a frequency of more than 14 hot flashes per week (2 times per day) in the week before inclusion in the study, the weekly average hot flash composite score is 3-4;
Patients after surgery and chemotherapy (if any);
Tumor metastases, undergoing chemoradiotherapy or planning surgery;
Pharmacological intervention for hot flashes with hot flash treatment drugs such as selective serotonin reuptake inhibitors (SSRIs) and/or anticonvulsants for at least 4 weeks prior to study initiation;
Patients receiving phytoestrogens, tibolone or analogs, verapril, or specific homeopathic medicines;
Started or changed adjuvant hormone therapy within the past week, or who planned to start or change adjuvant hormone therapy in the past 14 weeks, pregnant or breastfeeding patients;
Nanjing University of Traditional Chinese Medicine
Lead sponsor
Xi'an Jiaotong University
Collaborator
Hanzhong Hospital of Traditional Chinese Medicine
Collaborator
Xiang'an Hospital of Xiamen University
Collaborator
Dongzhimen Hospital, Beijing
Collaborator