Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

To evaluate the improvement of mitral regurgitation after catheter ablation of atrial fibrillation or regular drug therapy in atrial fibrillation patients combined with atrial functional mitral regurgitation.

Eligibility criteria

Qualifiers

Patients aged 18 to 80 years old;

Patients diagnosed with symptomatic paroxysmal atrial fibrillation (AF history < 5 years)

Moderate to severe MR and normal LV ejection fraction (≥50%), LVEDD<55 mm, and normal LV wall systolic function

Able to understand the purpose of the trial, participate in the trial voluntarily with informed consent form signed by the subject him/herself or his or her legal representative, and willing to complete follow-up visits as required under the protocol

Disqualifiers

Atrial fibrillation secondary to electrolyte imbalances, thyroid disease or other reversible factors

Active endocarditis or active rheumatic heart disease, or degenerative mitral regurgitation due to endocarditis or rheumatic valvular heart disease

Moderate to severe mitral stenosis

Imaging examination shows left atrium or left atrial appendage thrombosis

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

500 Participants
are grouped into 2 trial groups