Study of DIOSHA S Lido Injection vs. YOUTHFILL Fine With Lidocaine in Treating Moderate to Severe Nasolabial Folds
Adults aged 19 to 75 years
Voluntarily provided written informed consent
Moderate to severe symmetrical nasolabial folds (WSRS score 3 or 4 on both sides)
Agree to discontinue other facial dermatologic treatments (e.g., fillers, botulinum toxin, laser) during the study
Active facial skin disease, infection, or untreated scars in the treatment area
History of severe allergy or hypersensitivity to device components
Facial aesthetic or invasive procedures in the treatment area within 6 months prior to screening
Use of prohibited medications within required washout periods