Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.

ConditionLung Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age55-74
SponsorThe Institute of Molecular and Translational Medicine, Czech Republic

About this trial

The trial will evaluate if the newly identified biomarkers of lung cancer in exhaled breath condensate are as a diagnostic tool comparable to the low-dose computer tomography (LDCT) implemented in lung cancer screening recently. Due to the possibility to collect breath condensate at any medical workplace and due to the relatively low financial cost of examination of the collected breath condensate could improve early diagnosis of lung cancer, differential diagnostics of lung nodules and thereby reduce both the unnecessary interventions and deaths from this type of cancer.

Eligibility criteria

Qualifiers

Consent to participate in a clinical trial.

A clients within an age of 55-74 years.

priority will be given to clients who have smoked at least 30 pack-years.

preference will be given to a former smoker who has not smoked for less than 15 years.

Disqualifiers

Previous diagnosis of lung cancer.

Progressing malignant tumor on symptomatic treatment.

Advanced dementia

Chronic obstructive pulmonary disease or other inflammatory disease in the phase of acute exacerbation.

Trial design

Treatments tested in this trial

  • Exhaled breath condensate sampling
  • Blood sampling
  • LDCT
  • Vital signs
  • Spirometry

Treatment groups

3,200 Participants
are divided into 1 treatment group

Sponsors and collaborators