Alcoholic hepatitis carries a risk of high mortality at short term, especially in its severe form. Its diagnosis is confirmed by liver biopsy. The prevalence of alcoholic hepatitis, severe or not severe, is poorly known and prospective data are needed. The present observational study aims to define the prevalence of alcoholic hepatitis among patients admitted for jaundice and determine their outcome according to the severity. Survival and markers of liver dysfunction will be assessed. A biobank including genetic samples will be created to identify the disease profile in terms of inflammation and regeneration. The performance of non-invasive criteria for diagnosis will also be studied.
On average> 40 g / day for women and 50 g / day for men
Duration:> 5 years
Recent jaundice episode (less than 3 months)
Bilirubin> 50 mg / l (85μmol / l)
Presence of another hepatic pathology: evidenced by blood biology, imaging or histology (viral or autoimmune hepatitis, hemochromatosis, Wilson's disease)
Presence of hepatocellular carcinoma
HIV infection
History established / suggestive of HAA (Clinical, biological and / or histological criteria) in particular absence of jaundice episode