Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age35-70
SponsorSkolkovo Institute of Science and Technology

About this trial

The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy (fNIRS) in patients with hemiparesis after stroke. Participants in the study performed a simple stimulus-response task several times with one healthy and one paralyzed limb at different stages of basic rehabilitation. A group of healthy, age-matched volunteers participated in the same experiment to verify the stroke-related changes. The researchers recorded fNIRS signals, muscle activity using electromyography, and heart activity using electrocardiography.

Eligibility criteria

Qualifiers

None

Disqualifiers

The presence of superficial injury of head (S00-S09 International Classification of Diseases 10 (ICD-10).

The presence of mental, behavioural disorders (F00-F99 ICD-10).

Drug addiction in the past or at the moment.

The presence of diseases of the nervous system (G00-G99 ICD-10).

Trial design

Treatments tested in this trial

  • Stimulus response task

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Skolkovo Institute of Science and Technology

Lead sponsor

Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency of Russia

Collaborator