Study of JTM104 Injection vs. Juvederm in Treating Moderate to Severe Nasolabial Folds
Adults aged 19 to 75 years
Voluntarily provided written informed consent
Moderate to severe symmetrical nasolabial folds (WSRS score 3 or 4 on both sides)
Agree to discontinue other facial dermatologic treatments (e.g., fillers, botulinum toxin, laser) during the study
Untreated scars or facial skin infections/diseases affecting the mid/lower face within the past year
History of severe allergy or hypersensitivity to device components
Facial invasive procedures within the past 6 months (including surgery, laser, botulinum toxin)
Use of certain medications (anticoagulants, immunosuppressants, steroids) within specified washout periods