Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With Psychosis

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16-55
SponsorCentre Psychothérapique de Nancy

About this trial

This research concerns the study of language disorders of patients present in the spectrum of psychosis. It is indeed accepted that psychotic disorders are associated with language difficulties, which are only poorly highlighted thanks to reusable tools in clinical practice. These language disorders impact communication, and concern many linguistic domains, thus covering phonology, lexicon, semantics, morphosyntax and pragmatics. It therefore seems relevant to characterize these language disorders and to assess to what extent they interact with the other symptoms of the pathology, in particular the course of the thought disorder and the neuropsychological symptoms. In addition, this study is particularly interested in the interactions between working memory capacities and those related to syntax. It is intended for different patients suffering from psychotic disorders of different intensities, treated in the Psychotherapeutic Center of Nancy. Patients suffering from at-risk mental state (ARMS), first episode of psychosis (FEP) or schizophrenia will benefit from a complete language assessment, evaluating each domain mentioned above, on the expressive and understanding sides. The results of the language assessment will be compared with those of a control group in the same tests. They will also be analyzed with regard to the neuropsychological and psychiatric elements noted in the patient's medical file, in order to highlight possible associations between language skills, neuropsychological and psychiatric symptoms in this patient population.

Eligibility criteria

Qualifiers

Patient affiliated or entitled to a social security scheme

Patient having received informed information on the study and having co-signed, with the investigator, a consent to participate in the study

For minor participants, at least one of the parents or holders of parental authority having been informed of the study, having received the information note relating to it and not having objected to the participation of his or her child

Native language: French

Disqualifiers

Pregnant, parturient or nursing mother

Person deprived of liberty by a judicial or administrative decision

Person in a life-threatening emergency

Adult subject to a legal protection measure (guardianship, curatorship, safeguard of justice)

Trial design

Treatments tested in this trial

  • Language assessment
  • TLC - Scale for the Assessment of Thought, Language, and Communication
  • MINI - Mini International Neuropsychiatric Interview
  • CAST - Cannabis Abuse Screening Test

Treatment groups

90 Participants
are divided into 3 treatment groups