Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Tours

About this trial

This study evaluates the variation of expression of the neonatal Fc receptor (FcRn) in Natural Killer T Cells Expressing an Invariant T Receptor (iNKT) and monocytes along with the surface expression of Fc gamma type II receptor (RII) and RIII in active or newly diagnosed lupus patients compared to inactive lupus patients.

Eligibility criteria

Qualifiers

Age ≥ 18 years

Diagnosis of definite systemic lupus which may be associated with secondary antiphospholipid syndrome and/or secondary Gougerot-Sjögren's

Lupus patient, newly diagnosed or known, untreated or in relapse

Lupus patient considered stable by the treating practitioner

Disqualifiers

Main autoimmune disease other than lupus

Patient under legal protection, guardianship or curators

Opposition to data processing

Trial design

Treatments tested in this trial

  • Blood sample

Treatment groups

50 Participants
are divided into 1 treatment group

Sponsors and collaborators

University Hospital, Tours

Lead sponsor

Research Center for Respiratory Diseases, Inserm U1100

Collaborator