Study of Nimotuzumab Combined With IMRT in Elder Patients With Cervical Squamous Cell Carcinoma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age65+
SponsorPeking University Third Hospital

About this trial

To evaluate the efficacy and safety of Nimotuzumab combined with IMRT in elder patients with locally advanced cervical squamous cell carcinoma

Eligibility criteria

Qualifiers

Age≥65 years old

Histologically confirmed primary cervical squamous cell carcinoma in stage IB3-IVA (FIGO 2018)

At least one measurable lesion according to RECIST 1.1 guideline

Patients are intolerant to or refuse chemotherapy.

Disqualifiers

Patients who have received treatment for cervical cancer, including surgery, radiotherapy, chemotherapy, targeted therapy and immunotherapy

Patients who have bilateral ureteral obstruction, who cannot be placed ureteral stents or perform pyelostomy.

Patients with rectovaginal fistula/vaginovesical fistula/uncontrolled vaginal bleeding or with fistula risk.

Trial design

Treatments tested in this trial

  • Nimotuzumab
  • EBRT combined with brachytherapy

Treatment groups

125 Participants
are divided into 1 treatment group