Study of Parameters of Osteosarcopenia in Patients With Hip Fracture
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorIstituto Ortopedico Rizzoli
About this trial
The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck. The control group will consist of patients undergoing a hip replacement for osteoarthritis, as the decrease in muscle function and bone quality is less severe in this condition than in osteoporosis.
Eligibility criteria
Qualifiers
Patients who came to observation with femoral neck fracture of possible osteoporotic nature (no or minimal trauma) to be treated with endoprosthesis or hip arthroplasty.
Competent patients who have signed consent to participate in the study (see Informed Consent section of this protocol).
Disqualifiers
Previous osteoporotic fractures
Previous prosthetic surgery for orthopedic diseases
Pre-existing clinical conditions that led to permanent immobility
Neoplastic diseases
Trial design
Treatments tested in this trial
- SARC-F questionnaire
- Bone tissue histology
- Muscle tissue histology
- Myostatin serum levels
- Insulin-like growth factor 1 (IGF-1) serum levels
- Frequency food questionnaire
- Gut microbiota profiling
Treatment groups
100 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov