Metabolic Dysfunction Associated Liver Disease (MASLD) is associated with metabolic syndrome, and PNPLA3 variants are known to be implicated in intrahepatic lipid accumulation and linked to lipotoxicity. Analysis of PNPLA3 polymorphisms in an overseas territories population of MASLD would be interesting to describe their profile susceptibility to develop Metabolic dysfunction associated steatohepatitis (MASH).
Patients affiliated with, or beneficiaries of, a social security scheme.
Free, informed, and written consent obtained from the participant and signed by both the participant and the investigator (no later than the day of inclusion and prior to any procedure required by the study).
Patients under 18 years of age.
Patients unable to provide informed consent; so-called vulnerable populations (individuals under guardianship, judicial protection, etc.).
Centre Hospitalier Universitaire de la Guadeloupe
Lead sponsor
Centre Hospitalier Universitaire de la Réunion
Collaborator