Multicenter, non-interventional, retrospective/prospective study of a biological nature, on patients affected by head and neck tumors, for which the collection and use of tissue samples is planned for the study of the mutational profile, the transcriptional profile and the proteomic profile.
Age over 18
Patients with squamous cell tumors of the oral cavity, pharynx or larynx
Surgical patients with primary HNSCC tumors, who have not had previous tumors in other sites or adjuvant treatments prior to surgery.
Availability of adequate material (tissue) for the planned analyses
Presence of distant metastases at the time of diagnosis
Previous head and neck cancer
Second cancer undergoing treatment or follow-up for less than 5 years