Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection

ConditionPre-Eclampsia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorCentre Hospitalier Intercommunal Creteil

About this trial

Preeclampsia and intrauterine growth retardation (IUGR) are serious and frequent pathologies, specific to pregnancy. They represent 70 000 new cases a year, or 9% of pregnancies and cause 50,000 premature births per year in France. The consequences in terms of morbidity and perinatal morbidity and the medical and economic costs make it an issue public health. Pre-eclampsia associates maternal hypertension with dysfunction kidney. There is no cure for pre-eclampsia or IUGR vascular during pregnancy. These pathologies invariably evolve towards a maternal and / or fetal aggravation sometimes very fast. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary for the development of supported medical, obstetric and pediatric that will improve the state of health maternal and neonatal

Eligibility criteria

Qualifiers

pregnant women

With or without vascular pathology

Disqualifiers

refusal to participate

multiple pregnancy

major fetal malformation diagnosed during pregnancy follow-up

Trial design

Treatments tested in this trial

  • collect of placenta, blood and urinary samples at delivery

Treatment groups

500 Participants
are divided into 2 treatment groups