Study on the Contribution of the Genetic Tumor Profile Obtained by Circulating Tumor DNA Analysis in the Multidisciplinary Molecular Biology Meeting of Eastern PACA

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Antoine Lacassagne

About this trial

This study will evaluate the diagnostic performance of liquid biopsy for identifying molecular abnormalities among patients managed by the Multidisciplinary Molecular Biology Meeting. The gold standard considered in this study is the solid biopsy.

Eligibility criteria

Qualifiers

Over 18 years old.

Advanced-stage malignant solid tumor managed in a non-curative context.

Patient eligible for Multidisciplinary molecular biology meeting with available archived tumor material (frozen or FFPE block, less than 5 years old) or a biopsiable tumor lesion.

Performance status of 0 or 1.

Disqualifiers

Previous or concurrent cancer diagnosed or treated within the last 5 years, except for in situ carcinoma of the cervix, basal cell or squamous cell carcinoma of the skin, and adequately treated in situ carcinoma of the bladder.

Severe or uncontrolled systemic disease.

Any condition which, in the investigator's judgment (geographical, social, or psychological factors, etc.), makes the patient unable to comply with study follow-up and procedures.

Pregnant women, women in labor, and breastfeeding mothers,

Trial design

Treatments tested in this trial

  • Blood sample taken for the liquid biopsy

Treatment groups

238 Participants
are divided into 1 treatment group

Sponsors and collaborators