About this trial
Investigating the efficacy and safety of temporal interference stimulation for patients with disorders of consciousness.
Eligibility criteria
Qualifiers
Severe consciousness disorder patients aged 18 to 75 years old, regardless of gender;
Patients with severe consciousness disorders, namely a minimally conscious state or vegetative state that lasts for 28 days or more;
Patients with normal body temperature, stable vital signs, spontaneous breathing, tracheotomy without the use of a metal cannula and with a small amount of sputum, and who are eligible for magnetic resonance imaging (MRI) examination;
Written informed consent obtained from the patient's family members in advance.
Disqualifiers
Individuals with a previous history of significant neuropsychiatric and other major disorders such as those involving the heart, lung, liver, and kidney;
Those who have undergone V-P shunt or Ommaya reservoir implantation and other procedures that may influence the analysis of magnetic resonance scanning signals;
Patients who are scheduled for V-P shunt or Ommaya reservoir implantation in the near future;
Pregnant women;
Trial design
Treatments tested in this trial
- TI Stimulation
- Sham Stimulation
Treatment groups
Sponsors and collaborators
Huashan Hospital
Lead sponsor
Shanghai First Rehabilitation Hospital
Collaborator