Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated with Anti-EGFR

ConditionXerosis Cutis

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorSocieta Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse

About this trial

Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated With Anti-EGFR.

Eligibility criteria

Qualifiers

patients aged 18 who have been receiving anti-EGFR therapy for more than three months,

signature of the informed consent.

Disqualifiers

Patients diagnosed with Grade II papulopustulous skin reaction according to the Common Terminology Criteria for Adverse Event (CTCAE) scale at the time of enrolment;

concomitant use of emollients and/or steroidal creams;

personal history of xerotic pathologies (e.g. lichen, ichthyosis) and/or itching of n.d.d.;

inability to provide informed consent or inability to complete the procedures required for enrollment in the study.

Trial design

Treatments tested in this trial

topical treatment with the pre- and postbiotic study preparation and niacinamide 4% and one with the 10% urea-based preparation.

Treatment groups

164 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse

Lead sponsor

Source ClinicalTrials.gov