This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery. The primary objectives are to determine:
Which analgesic regimen is most effective in reducing postoperative pain? Which analgesic regimen is most effective in accelerating gastrointestinal function recovery? This study will compare epidural analgesia (EA), paravertebral block (PB), transversus abdominis plane block (TAP), and patient-controlled intravenous analgesia (PCIA) to identify the optimal method for pain control and the most beneficial for gastrointestinal recovery.
Participants will receive one of the following treatments postoperatively: epidural analgesia, paravertebral block, TAP block, or patient-controlled intravenous analgesia. Rest pain (measured using the Numerical Rating Scale, NRS), dynamic pain (NRS), morphine equivalent consumption (mg), quality of sleep on the first night (Likert scale, 1-5), time to return of bowel function (h), time to recommence oral intake (h), time to first mobilization (h), quality of recovery (QoR, 0-15) on postoperative day 1, and length of hospital stay (days) will be recorded at 4, 8, 12, and 24 hours post-procedure.
>18 years old
ASA I-III
Ability to understand and voluntarily sign the informed consent form
No prior use of long-acting or addictive analgesic drugs before surgery.
History of previous abdominal surgery
Presence of severe cardiovascular, respiratory, hepatic, renal, neurological, or psychiatric disorders
Pre-existing chronic pain conditions
Known allergy to any analgesic drugs used in this study
Xiaguang Duan
Lead sponsor
Inner Mongolia Baogang Hospital
Sponsor institution