This randomized controlled clinical trial aims to evaluate the effect of electroacupuncture combined with self-acupressure on the quality of life of early-stage breast cancer patients receiving chemotherapy.
Aged 18 years or older and aged 75 years or younger, inclusive. with an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2;
Patients who have not received prior chemotherapy and are scheduled to receive at least 4 cycles of adjuvant or neoadjuvant chemotherapy or combination targeted therapy;
Normal organ function with platelets ≥ 100*10^9/ L, hemoglobin ≥ 90 g/L, serum creatinine ≤ 1.5 mg/dl (133 mmol/L), or creatinine clearance ≥ 60 ml/min, total bilirubin ≤ 1.5 times the upper limit of normal (ULN), alanine aminotransferase ≤ 2.5 times ULN, and aspartate aminotransferase ≤ 2.5 times ULN;
Premenopausal women need appropriate contraception;
Patients with needle phobia or allergy to stainless steel needles; and
Current diagnosis of mental illness (e.g., major depression, obsessive-compulsive disorder, or schizophrenia);
History of autoimmune diseases, blood disorders, or organ transplantation, or long-term use of hormones or immunosuppressants;
Comorbid bleeding disorders or thyroid dysfunction;
Jiuda Zhao
Lead sponsor
Affiliated Hospital of Qinghai University
Sponsor institution