To evaluate the safety and clinical efficacy of left atrial appendage in the prevention of thrombus in patients with valvular heart disease, to improve the product according to clinical conditions, to achieve clinically accurate treatment, and to establish the heart valve, the usefulness and universality of Warfarin's anticoagulant model were verified by the specimen library
Patients with valvular heart disease aged between 18 and 75
Valvular heart disease [Cardiovascular Surgery Volume, Clinical Diagnosis and Treatment Guidelines, Chinese Medical Association (2011 edition)]
Preoperative cardiac function grade II-III (NYHA), no operation-related contraindications
Understand the nature of this study, agree to participate in all terms of this study, sign informed consent, agree to accept postoperative treatment plan and follow-up requirements, and cooperate to complete follow-up
Patients whose left atrial appendage has been resected or occluded
She had a history of open heart surgery with extensive adhesion of the pericardium
Patients cannot be returned due to other reasons
Failed to reach the end point in clinical trials of other drugs or devices