Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer
ConditionGastric Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorYunnan Cancer Hospital
About this trial
Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.
This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients.
A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.
Eligibility criteria
Qualifiers
The patient was diagnosed with gastric cancer by pathological biopsy
No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.
Disqualifiers
The image quality cannot meet the diagnostic criteria;
Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.
Trial design
Treatments tested in this trial
- Scanning parameter
Treatment groups
129 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov