Study to Determine the Antitumor Activity of New CAR-macrophages in Breast Cancer Patients' Derived Organoids

ConditionBreast Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorCentre Oscar Lambret

About this trial

Cell-based immune therapy using modified macrophages is a promising therapeutic approach in breast cancer. The objective of this cohort study is to collect tumor samples to develop patients' derived organoids to test the antitumor activity of newly developed CAR-macrophages. Other biological samples will be collected such as blood to analyze the host inflammatory status.

Eligibility criteria

Qualifiers

Male or female aged 18 years or more

Histologically confirmed breast cancer at any stage

Requiring surgery or tumor biopsy as standard of care

Any or no systemic treatment

Disqualifiers

Opposed to biospecimen collection

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

Centre Oscar Lambret

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Collaborator