About this trial
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease. This pilot study aims to show the interest of alternative non-pharmacological measures such as a digital music therapy tool, adapted to an audience of Huntington's patients, to help manage the psychobehavioral symptoms frequently observed in this affection, and to avoid breakdowns due to caregiver exhaustion.
Eligibility criteria
Qualifiers
Age >= 18 years
Huntington disease genetically confirmed by the presence of at least 35 repeats of the CAG triplet in exon 1 of the HTT gene
UHDRS (Unified Huntington's disease Rating Scale) score <= 5 with a diagnostic confidence score =4
Absence of significant cognitive impairment MoCA >=24
Disqualifiers
Inability to give free and informed consent for study participation
Significant hearing impairment
Participating to another study the day of enrollement
Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.
Trial design
Treatments tested in this trial
- Music Intervention