Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorPoitiers University Hospital

About this trial

The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease. This pilot study aims to show the interest of alternative non-pharmacological measures such as a digital music therapy tool, adapted to an audience of Huntington's patients, to help manage the psychobehavioral symptoms frequently observed in this affection, and to avoid breakdowns due to caregiver exhaustion.

Eligibility criteria

Qualifiers

Age >= 18 years

Huntington disease genetically confirmed by the presence of at least 35 repeats of the CAG triplet in exon 1 of the HTT gene

UHDRS (Unified Huntington's disease Rating Scale) score <= 5 with a diagnostic confidence score =4

Absence of significant cognitive impairment MoCA >=24

Disqualifiers

Inability to give free and informed consent for study participation

Significant hearing impairment

Participating to another study the day of enrollement

Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.

Trial design

Treatments tested in this trial

  • Music Intervention

Treatment groups

15 Participants
are divided into 1 treatment group

Sponsors and collaborators