Study to Evaluate the Efficacy of a Polyamine-deficient Diet for Treating Postoperative Pain After Abdominal Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNantes University Hospital

About this trial

The aim of this study is to evaluate if a polyamine deficient diet started 7 days prior to a major abdominal surgery (eventration cure and digestive continuity) and followed 7 days post-surgery reduces the area under the curve of the numerical pain rating scale in the 72 hours post-surgery.

Eligibility criteria

Qualifiers

Adult (>18 years)

Indication for a " major " abdominal surgery as second surgical procedure : cure of eventration and restoration of digestive continuity

Intended Use of a Patient Controlled Morphine Pump (PCA) postoperatively or taking oral opioids

Possible follow-up during 7 months (post-operative consultation at 1 month and 6 months only if postoperative pain or complications)

Disqualifiers

Pregnant women

Minor, adult under guardianship or benefiting from a legal protection

Oncological surgery

Surgery not painful (cholecystectomy, hernia, thyroidectomy, bariatric surgery)

Trial design

Treatments tested in this trial

  • Polyamine Deficient Diet

Treatment groups

278 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Nantes University Hospital

Lead sponsor

Centre de Recherche en Nutrition Humaine Ouest (CRNH)

Collaborator