About this trial
The aim of this study is to evaluate if a polyamine deficient diet started 7 days prior to a major abdominal surgery (eventration cure and digestive continuity) and followed 7 days post-surgery reduces the area under the curve of the numerical pain rating scale in the 72 hours post-surgery.
Eligibility criteria
Qualifiers
Adult (>18 years)
Indication for a " major " abdominal surgery as second surgical procedure : cure of eventration and restoration of digestive continuity
Intended Use of a Patient Controlled Morphine Pump (PCA) postoperatively or taking oral opioids
Possible follow-up during 7 months (post-operative consultation at 1 month and 6 months only if postoperative pain or complications)
Disqualifiers
Pregnant women
Minor, adult under guardianship or benefiting from a legal protection
Oncological surgery
Surgery not painful (cholecystectomy, hernia, thyroidectomy, bariatric surgery)
Trial design
Treatments tested in this trial
- Polyamine Deficient Diet
Treatment groups
Sponsors and collaborators
Nantes University Hospital
Lead sponsor
Centre de Recherche en Nutrition Humaine Ouest (CRNH)
Collaborator