Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorVrije Universiteit Brussel

About this trial

This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain. Specifically, this study aims to evaluate the neurobiological mechanisms underlying the relationship between chronic sleep disturbances and pain sensitivity in people with non-specific chronic low back pain and chronic insomnia.

Eligibility criteria

Qualifiers

18-60 years old.

Ability to speak and understand the Dutch Language.

Body mass index <30.

No smoking or nicotine use.

Disqualifiers

Shift worker.

Use of blood thinners.

(History of) Substance dependence/abuse.

Chronic pain conditions (≥3 months) other than chronic low back pain.

Trial design

Treatments tested in this trial

  • Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.

Treatment groups

80 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Vrije Universiteit Brussel

Lead sponsor

Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek)

Collaborator

Universitaire Ziekenhuizen KU Leuven

Collaborator